Reaction Details Report a problem with these data
Target
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Ligand
BDBM50615551
Substrate
n/a
Meas. Tech.
ChEMBL_2302768
Ki
18±n/a nM
Citation
 Govindarajan, M Amphiphilic glycoconjugates as potential anti-cancer chemotherapeutics. Eur J Med Chem 143:1208-1253 (2018) [PubMed] 
Target
Name:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Synonyms:
AT2A1_RABIT | ATP2A1 | Sarco/endoplasmic Reticulum Ca2+ ATPase 1 | Sarcoplasmic/endoplasmic reticulum calcium ATP-ase
Type:
PROTEIN
Mol. Mass.:
110435.34
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_1500621
Residue:
1001
Sequence:
MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEDPEDERRK
  
Inhibitor
Name:
BDBM50615551
Synonyms:
CHEMBL5268892
Type:
Small organic molecule
Emp. Form.:
C34H52O11
Mol. Mass.:
636.7701
SMILES:
[H][C@@]12C[C@H](C)\C=C(C)\[C@H](C\C=C\[C@H](CC(=O)O[C@H](C[C@]([H])(OO1)C=C2)\C=C(\C)C\C=C\C)O[C@]1([H])O[C@H](CO)[C@@H](O)[C@H](OC)[C@H]1O)OC |r,c:5,24,t:10|
Structure:
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