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Target
NAD kinase
Ligand
BDBM50203628
Substrate
n/a
Meas. Tech.
ChEMBL_441951 (CHEMBL891095)
Ki
90000±n/a nM
Citation
 Bonnac, L; Chen, L; Pathak, R; Gao, G; Ming, Q; Bennett, E; Felczak, K; Kullberg, M; Patterson, SE; Mazzola, F; Magni, G; Pankiewicz, KW Probing binding requirements of NAD kinase with modified substrate (NAD) analogues. Bioorg Med Chem Lett 17:1512-5 (2007) [PubMed]  Article 
Target
Name:
NAD kinase
Synonyms:
NADK | NADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
49227.18
Organism:
Homo sapiens (Human)
Description:
ChEMBL_578494
Residue:
446
Sequence:
MEMEQEKMTMNKELSPDAAAYCCSACHGDETWSYNHPIRGRAKSRSLSASPALGSTKEFRRTRSLHGPCPVTTFGPKACVLQNPQTIMHIQDPASQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEENMIVYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFEEEEEEEEEG
  
Inhibitor
Name:
BDBM50203628
Synonyms:
Benzamide adenine dinucleotide | CHEMBL233434 | benzamideadeninedinucleoside
Type:
Small organic molecule
Emp. Form.:
C22H28N6O14P2
Mol. Mass.:
662.437
SMILES:
NC(=O)c1cccc(c1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |w:18.19,14.15|
Structure:
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