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Target
Delta-type opioid receptor
Ligand
BDBM50203828
Substrate
n/a
Meas. Tech.
ChEMBL_425710 (CHEMBL913692)
IC50
>10000±n/a nM
Citation
 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2). J Med Chem 50:512-20 (2007) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50203828
Synonyms:
CHEMBL375069 | Tyr-Pro-Phe-D-1-Nal-NH2
Type:
Small organic molecule
Emp. Form.:
C36H39N5O5
Mol. Mass.:
621.7254
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O
Structure:
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