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Target
Cannabinoid receptor 2
Ligand
BDBM50205169
Substrate
n/a
Meas. Tech.
ChEMBL_438314 (CHEMBL887422)
IC50
283.5±n/a nM
Citation
 Armstrong, HE; Galka, A; Lin, LS; Lanza, TJ; Jewell, JP; Shah, SK; Guthikonda, R; Truong, Q; Chang, LL; Quaker, G; Colandrea, VJ; Tong, X; Wang, J; Xu, S; Fong, TM; Shen, CP; Lao, J; Chen, J; Shearman, LP; Stribling, DS; Rosko, K; Strack, A; Ha, S; Van der Ploeg, L; Goulet, MT; Hagmann, WK Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists. Bioorg Med Chem Lett 17:2184-7 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50205169
Synonyms:
2,6-dichloro-N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)benzenesulfonamide | CHEMBL230506
Type:
Small organic molecule
Emp. Form.:
C23H19Cl3N2O2S
Mol. Mass.:
493.833
SMILES:
C[C@H](NS(=O)(=O)c1c(Cl)cccc1Cl)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N
Structure:
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