Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50213154
Substrate
n/a
Meas. Tech.
ChEMBL_447434 (CHEMBL896458)
Ki
55±n/a nM
Citation
 Worm, K; Zhou, QJ; Stabley, GJ; DeHaven, RN; Dolle, RE Biaryl cannabinoid mimetics--synthesis and structure-activity relationship. Bioorg Med Chem Lett 17:3652-6 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50213154
Synonyms:
4-(1-hexyl-cyclopropyl)-3',5'-dimethyl-biphenyl-2-ol | CHEMBL233633
Type:
Small organic molecule
Emp. Form.:
C23H30O
Mol. Mass.:
322.4837
SMILES:
CCCCCCC1(CC1)c1ccc(c(O)c1)-c1cc(C)cc(C)c1
Structure:
Search PDB for entries with ligand similarity: