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Target
Cannabinoid receptor 2
Ligand
BDBM50213615
Substrate
n/a
Meas. Tech.
ChEMBL_456159 (CHEMBL888168)
Ki
187±n/a nM
Citation
 Kai, H; Morioka, Y; Murashi, T; Morita, K; Shinonome, S; Nakazato, H; Kawamoto, K; Hanasaki, K; Takahashi, F; Mihara, S; Arai, T; Abe, K; Okabe, H; Baba, T; Yoshikawa, T; Takenaka, H 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: discovery of CB2 receptor selective compounds. Bioorg Med Chem Lett 17:4030-4 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50213615
Synonyms:
(Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-1,3-thiazinane-3-carboxylate | CHEMBL248135
Type:
Small organic molecule
Emp. Form.:
C18H26N2O2S
Mol. Mass.:
334.476
SMILES:
CCOC(=O)N1CC(C)(C)CS\C1=N/c1ccccc1C(C)C
Structure:
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