Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50213886
Substrate
n/a
Meas. Tech.
ChEMBL_447530 (CHEMBL896544)
Ki
6.8±n/a nM
Citation
 Kai, H; Morioka, Y; Tomida, M; Takahashi, T; Hattori, M; Hanasaki, K; Koike, K; Chiba, H; Shinohara, S; Kanemasa, T; Iwamoto, Y; Takahashi, K; Yamaguchi, Y; Baba, T; Yoshikawa, T; Takenaka, H 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: orally bioavailable compounds. Bioorg Med Chem Lett 17:3925-9 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1
Type:
Enzyme
Mol. Mass.:
52842.52
Organism:
Mus musculus (Mouse)
Description:
P47746
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50213886
Synonyms:
3-[(Z)-naphthalen-1-ylimino]-2-thia-4-aza-spiro[5.5]undecane-4-carbodithioic acid methyl ester | CHEMBL232328 | methyl 3-(naphthalen-1-ylimino)-2-thia-4-azaspiro[5.5]undecane-4-carbodithioate
Type:
Small organic molecule
Emp. Form.:
C21H24N2S3
Mol. Mass.:
400.624
SMILES:
CSC(=S)N1CC2(CCCCC2)CS\C1=N/c1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: