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Target
Cannabinoid receptor 1
Ligand
BDBM50213904
Substrate
n/a
Meas. Tech.
ChEMBL_447526 (CHEMBL895425)
Ki
95±n/a nM
Citation
 Kai, H; Morioka, Y; Tomida, M; Takahashi, T; Hattori, M; Hanasaki, K; Koike, K; Chiba, H; Shinohara, S; Kanemasa, T; Iwamoto, Y; Takahashi, K; Yamaguchi, Y; Baba, T; Yoshikawa, T; Takenaka, H 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: orally bioavailable compounds. Bioorg Med Chem Lett 17:3925-9 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50213904
Synonyms:
3-[(Z)-4-ethyl-phenylimino]-2-thia-4-aza-spiro[5.5]undecane-4-carbodithioic acid methyl ester | CHEMBL392842
Type:
Small organic molecule
Emp. Form.:
C19H26N2S3
Mol. Mass.:
378.618
SMILES:
CCc1ccc(cc1)\N=C1/SCC2(CCCCC2)CN1C(=S)SC
Structure:
Search PDB for entries with ligand similarity: