Reaction Details Report a problem with these data
Target
Bcl2-associated agonist of cell death
Ligand
BDBM50214871
Substrate
n/a
Meas. Tech.
ChEMBL_439338 (CHEMBL888454)
Ki
1200±n/a nM
Citation
Tang, G; Ding, K; Nikolovska-Coleska, Z; Yang, CY; Qiu, S; Shangary, S; Wang, R; Guo, J; Gao, W; Meagher, J; Stuckey, J; Krajewski, K; Jiang, S; Roller, PP; Wang, S Structure-based design of flavonoid compounds as a new class of small-molecule inhibitors of the anti-apoptotic Bcl-2 proteins. J Med Chem 50:3163-6 (2007) [PubMed] Article
More Info.:
Target
Name:
Bcl2-associated agonist of cell death
Synonyms:
BAD | BAD_HUMAN | BBC6 | BCL2L8 | Bcl-2-binding component 6 | Bcl-2-like protein 8 | Bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8 | Bcl2-antagonist of cell death (BAD)
Type:
PROTEIN
Mol. Mass.:
18393.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_478760
Residue:
168
Sequence:
MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSHHGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ