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Target
D(3) dopamine receptor
Ligand
BDBM50216053
Substrate
n/a
Meas. Tech.
ChEMBL_448359 (CHEMBL898620)
Ki
102±n/a nM
Citation
 Awadallah, FM; Müller, F; Lehmann, J; Abadi, AH Synthesis of novel lactam derivatives and their evaluation as ligands for the dopamine receptors, leading to a D(4)-selective ligand. Bioorg Med Chem 15:5811-8 (2007) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50216053
Synonyms:
3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-quinazolin-4(3H)-one | CHEMBL398813
Type:
Small organic molecule
Emp. Form.:
C23H25F3N4O
Mol. Mass.:
430.466
SMILES:
FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1
Structure:
Search PDB for entries with ligand similarity: