Reaction Details Report a problem with these data
Target
Deoxyhypusine synthase
Ligand
BDBM50216786
Substrate
n/a
Meas. Tech.
ChEMBL_437263 (CHEMBL906657)
Ki
100±n/a nM
Citation
 Kaiser, A; Hammels, I; Gottwald, A; Nassar, M; Zaghloul, MS; Motaal, BA; Hauber, J; Hoerauf, A Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties. Bioorg Med Chem 15:6200-7 (2007) [PubMed]  Article 
Target
Name:
Deoxyhypusine synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
57187.86
Organism:
Plasmodium falciparum
Description:
ChEMBL_437263
Residue:
496
Sequence:
MVDHVSFIEVNKIRSDDECDADSHNEGDNIEDAKASVFVKSSLIPEKTDVVKGLNFDKEVDLHEFINNYKYMGFQATNLGISIDEINKMIYYKYKDENIKSEPNNENNLNCNNVSEDLNKDQENHLYHYEKKKKSCIIWLSFTSNMISSGLREIFVYLAKNKFIDVVVTTAGGIEEDIIKCFSNTYIGDFNLNGKKLRKKGWNRIGNLIVPNDNYCKFEDWLQPILNKMLHEQNEKNEQMFLKKLEKRKKKYNNNKNKNDNNNDNDNVWGNEKNDQNENQYNQGQESFKKDSNIYTNDVSNKKNHINNYINNYDSDSDDQCDMYYLSPSEFINTLGKEINDESSLIYWCYKNDIPIFCPGLTDGSLGDNLFLHNYGKKIKNNLILDIVKDIKKINSLAMNCEKSGIIILGGGLPKHHVCNANLMRNGADFAVYVNTASEYDGSDSGANTTEALSWGKIKYGQTNNHVKVFGDATILFPLMVLNSFYLYDQKRKKDM
  
Inhibitor
Name:
BDBM50216786
Synonyms:
CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diaminoheptane
Type:
Small organic molecule
Emp. Form.:
C8H20N4
Mol. Mass.:
172.2712
SMILES:
[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7]
Structure:
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