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Target
Adenosine receptor A1
Ligand
BDBM50219388
Substrate
n/a
Meas. Tech.
ChEMBL_457192 (CHEMBL940793)
Ki
290±n/a nM
Citation
 Gregg, A; Bottle, SE; Devine, SM; Figler, H; Linden, J; White, P; Pouton, CW; Urmaliya, V; Scammells, PJ Dual acting antioxidant A1 adenosine receptor agonists. Bioorg Med Chem Lett 17:5437-41 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50219388
Synonyms:
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(1,1,3,3-tetramethylisoindolin-5-ylamino)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol | CHEMBL249294
Type:
Small organic molecule
Emp. Form.:
C22H28N6O4
Mol. Mass.:
440.4955
SMILES:
CC1(C)NC(C)(C)c2cc(Nc3ncnc4n(cnc34)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)ccc12
Structure:
Search PDB for entries with ligand similarity: