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Target
D(1A) dopamine receptor
Ligand
BDBM50220545
Substrate
n/a
Meas. Tech.
ChEMBL_457315 (CHEMBL941848)
Ki
17000±n/a nM
Citation
 Stark, D; Piel, M; Hübner, H; Gmeiner, P; Gründer, G; Rösch, F In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors. Bioorg Med Chem 15:6819-29 (2007) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50220545
Synonyms:
CHEMBL397592 | N-(((S)-1-allylpyrrolidin-2-yl)methyl)-5-bromo-2-methoxybenzamide
Type:
Small organic molecule
Emp. Form.:
C16H21BrN2O2
Mol. Mass.:
353.254
SMILES:
COc1ccc(Br)cc1C(=O)NC[C@@H]1CCCN1CC=C
Structure:
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