Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50220545
Substrate
n/a
Meas. Tech.
ChEMBL_457318 (CHEMBL941851)
Ki
22±n/a nM
Citation
 Stark, D; Piel, M; Hübner, H; Gmeiner, P; Gründer, G; Rösch, F In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors. Bioorg Med Chem 15:6819-29 (2007) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50220545
Synonyms:
CHEMBL397592 | N-(((S)-1-allylpyrrolidin-2-yl)methyl)-5-bromo-2-methoxybenzamide
Type:
Small organic molecule
Emp. Form.:
C16H21BrN2O2
Mol. Mass.:
353.254
SMILES:
COc1ccc(Br)cc1C(=O)NC[C@@H]1CCCN1CC=C
Structure:
Search PDB for entries with ligand similarity: