Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM50183248
Substrate
n/a
Meas. Tech.
ChEMBL_457563 (CHEMBL922763)
IC50
>100000±n/a nM
Citation
 Moon, TC; Quan, Z; Kim, J; Kim, HP; Kudo, I; Murakami, M; Park, H; Chang, HW Inhibitory effect of synthetic C-C biflavones on various phospholipase A(2)s activity. Bioorg Med Chem 15:7138-43 (2007) [PubMed]  Article 
Target
Name:
Phospholipase A2
Synonyms:
PA21B_RAT | Phospholipase A2 group 1B | Pla2g1b
Type:
PROTEIN
Mol. Mass.:
16427.59
Organism:
Rattus norvegicus
Description:
ChEMBL_156506
Residue:
146
Sequence:
MKLLLLAALLTAGVTAHSISTRAVWQFRNMIKCTIPGSDPLREYNNYGCYCGLGGSGTPVDDLDRCCQTHDHCYNQAKKLESCKFLIDNPYTNTYSYKCSGNVITCSDKNNDCESFICNCDRQAAICFSKVPYNKEYKDLDTKKHC
  
Inhibitor
Name:
BDBM50183248
Synonyms:
2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-chromen-4-one | CHEMBL205219 | [4',4''']-biflavone
Type:
Small organic molecule
Emp. Form.:
C30H18O4
Mol. Mass.:
442.4615
SMILES:
O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc(cc1)-c1cc(=O)c2ccccc2o1
Structure:
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