Reaction Details Report a problem with these data
Target
Group 10 secretory phospholipase A2
Ligand
BDBM50183246
Substrate
n/a
Meas. Tech.
ChEMBL_457565 (CHEMBL922765)
IC50
27600±n/a nM
Citation
 Moon, TC; Quan, Z; Kim, J; Kim, HP; Kudo, I; Murakami, M; Park, H; Chang, HW Inhibitory effect of synthetic C-C biflavones on various phospholipase A(2)s activity. Bioorg Med Chem 15:7138-43 (2007) [PubMed]  Article 
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10
Type:
PROTEIN
Mol. Mass.:
18153.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1442449
Residue:
165
Sequence:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
  
Inhibitor
Name:
BDBM50183246
Synonyms:
6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chromen-4-one | CHEMBL383336 | [6,3''']biflavone
Type:
Small organic molecule
Emp. Form.:
C30H18O4
Mol. Mass.:
442.4615
SMILES:
O=c1cc(oc2ccccc12)-c1cccc(c1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1
Structure:
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