Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50221430
Substrate
n/a
Meas. Tech.
ChEMBL_457579 (CHEMBL922779)
Ki
360±n/a nM
Citation
 Vadivel, SK; Vardarajan, S; Duclos, RI; Wood, JT; Guo, J; Makriyannis, A Conformationally constrained analogues of 2-arachidonoylglycerol. Bioorg Med Chem Lett 17:5959-63 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50221430
Synonyms:
(5Z,8Z,11Z,14Z)-2,6-dihydroxycyclohexyl icosa-5,8,11,14-tetraenoate | CHEMBL246628
Type:
Small organic molecule
Emp. Form.:
C26H42O4
Mol. Mass.:
418.6093
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC1C(O)CCCC1O |w:22.21,23.23,28.29|
Structure:
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