Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50221711
Substrate
n/a
Meas. Tech.
ChEMBL_457679 (CHEMBL923956)
Ki
8.87±n/a nM
Citation
 Bourne, C; Roy, S; Wiley, JL; Martin, BR; Thomas, BF; Mahadevan, A; Razdan, RK Novel, potent THC/anandamide (hybrid) analogs. Bioorg Med Chem 15:7850-64 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50221711
Synonyms:
11-[3-(5-bromo-1,1-dimethylpentyl)phenoxy]-undeca-5,8-dienoic acid [R-(1-hydroxypropan-2-yl)]-amide | CHEMBL240314
Type:
Small organic molecule
Emp. Form.:
C27H42BrNO3
Mol. Mass.:
508.531
SMILES:
C[C@H](CO)NC(=O)CCC\C=C/C\C=C/CCOc1cccc(c1)C(C)(C)CCCCBr
Structure:
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