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Target
Chymotrypsin-like elastase family member 1
Ligand
BDBM50269564
Substrate
n/a
Meas. Tech.
ChEMBL_480219 (CHEMBL1019939)
Ki
290±n/a nM
Citation
 Song, KS; Raskin, I A prolyl endopeptidase-inhibiting benzofuran dimer from Polyozellus multiflex. J Nat Prod 65:76-8 (2002) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 1
Synonyms:
CELA1 | CELA1_HUMAN | ELA1 | Elastase 1 | Elastase-1
Type:
PROTEIN
Mol. Mass.:
27805.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_63626
Residue:
258
Sequence:
MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
  
Inhibitor
Name:
BDBM50269564
Synonyms:
5,6,5',6'-tetrahydroxy[3,3']bibenzofuranyl-2,2'-dicarboxylic acid dimethyl ester | CHEMBL465606
Type:
Small organic molecule
Emp. Form.:
C20H14O10
Mol. Mass.:
414.3192
SMILES:
COC(=O)c1oc2cc(O)c(O)cc2c1-c1c(oc2cc(O)c(O)cc12)C(=O)OC |(-3.37,-.48,;-1.83,-.48,;-1.06,.86,;-1.83,2.19,;.49,.86,;1.39,2.1,;2.85,1.63,;4.17,2.4,;5.5,1.64,;6.83,2.42,;5.51,.1,;6.85,-.67,;4.18,-.67,;2.85,.09,;1.39,-.39,;.64,-1.73,;1.55,-2.99,;.64,-4.24,;-.84,-3.76,;-2.17,-4.53,;-3.51,-3.76,;-4.84,-4.53,;-3.5,-2.22,;-4.84,-1.45,;-2.17,-1.45,;-.84,-2.21,;3.09,-2.99,;3.86,-1.65,;3.86,-4.32,;3.09,-5.65,)|
Structure:
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