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Target
Mobilization protein A
Ligand
BDBM50250671
Substrate
n/a
Meas. Tech.
ChEMBL_504678 (CHEMBL989451)
EC50
70000±n/a nM
Citation
 Chu, M; Mierzwa, R; Xu, L; He, L; Terracciano, J; Patel, M; Gullo, V; Black, T; Zhao, W; Chan, TM; McPhail, AT Isolation and structure elucidation of Sch 642305, a novel bacterial DNA primase inhibitor produced by Penicillium verrucosum. J Nat Prod 66:1527-30 (2003) [PubMed]  Article 
Target
Name:
Mobilization protein A
Synonyms:
MOBA2_ECOLX | mobA | repB
Type:
PROTEIN
Mol. Mass.:
77958.57
Organism:
Escherichia coli
Description:
ChEMBL_504678
Residue:
709
Sequence:
MAIYHLTAKTGSRSGGQSARAKADYIQREGKYARDMDEVLHAESGHMPEFVERPADYWDAADLYERANGRLFKEVEFALPVELTLDQQKALASEFAQHLTGAERLPYTLAIHAGGGENPHCHLMISERINDGIERPAAQWFKRYNGKTPEKGGAQKTEALKPKAWLEQTREAWADHANRALERAGHDARIDHRTLEAQGIERLPGVHLGPNVVEMEGRGIRTDRADVALNIDTANAQIIDLQEYREAIDHERNRQSEEIQRHQRVSGADRTAGPEHGDTGRRSPAGHEPDPAGQRGAGGGVAESPAPDRGGMGGAGQRVAGGSRRGEQRRAERPERVAGVALEAMANRDAGFHDAYGGAADRIVALARPDATDNRGRLDLAALGGPMKNDRTLQAIGRQLKAMGCERFDIGVRDATTGQMMNREWSAAEVLQNTPWLKRMNAQGNDVYIRPAEQERHGLVLVDDLSEFDLDDMKAEGREPALVVETSPKNYQAWVKVADAAGGELRGQIARTLASEYDADPASADSRHYGRLAGFTNRKDKHTTRAGYQPWVLLRESKGKTATAGPALVQQAGQQIEQAQRQQEKARRLASLELPERQLSRHRRTALDEYRSEMAGLVKRFGDDLSKCDFIAAQKLASRGRSAEEIGKAMAEASPALAERKPGHEADYIERTVSKVMGLPSVQLARAELARAPAPRQRGMDRGGPDFSM
  
Inhibitor
Name:
BDBM50250671
Synonyms:
(4S,8aR,12S,12aR)-12-hydroxy-4-methyl-4,5,6,7,8,8a-hexahydro-1H-benzo[d]oxecine-2,9(12H,12aH)-dione | CHEMBL453428 | SCH-642305
Type:
Small organic molecule
Emp. Form.:
C14H20O4
Mol. Mass.:
252.3062
SMILES:
C[C@H]1CCCC[C@@H]2[C@@H](CC(=O)O1)[C@@H](O)C=CC2=O |r,c:15|
Structure:
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