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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM50241707
Substrate
n/a
Meas. Tech.
ChEMBL_527197 (CHEMBL971986)
Ki
140±n/a nM
Citation
 Pereira, A; Vottero, E; Roberge, M; Mauk, AG; Andersen, RJ Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata. J Nat Prod 69:1496-9 (2006) [PubMed]  Article 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Homo sapiens (Human)
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM50241707
Synonyms:
CHEMBL518688 | annulin C | methyl 7-ethyl-8-hydroxy-1-methoxy-3,3,6-trimethyl-4,9-dioxo-1,3,4,9-tetrahydronaphtho[2,3-c]furan-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C20H22O7
Mol. Mass.:
374.3845
SMILES:
CCc1c(C)cc2C(=O)C3=C(C(=O)c2c1O)C(OC)(OC3(C)C)C(=O)OC |c:9|
Structure:
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