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Target
D(2) dopamine receptor
Ligand
BDBM50251026
Substrate
n/a
Meas. Tech.
ChEMBL_533450 (CHEMBL986942)
Ki
88±n/a nM
Citation
 Sipos, A; Csutorás, C; Berényi, S; Uustare, A; Rinken, A Synthesis and neuropharmacological characterization of 2-O-substituted apomorphines. Bioorg Med Chem 16:4563-8 (2008) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50251026
Synonyms:
(R)-(-)-2-Phenyl-apomorphine hydrochloride | CHEMBL458397 | CHEMBL465054
Type:
Small organic molecule
Emp. Form.:
C23H21NO2
Mol. Mass.:
343.4183
SMILES:
CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: