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Target
Pro-cathepsin H
Ligand
BDBM50186088
Substrate
n/a
Meas. Tech.
ChEMBL_518577 (CHEMBL959581)
Ki
3700±n/a nM
Citation
 Li, J; Petrassi, HM; Tumanut, C; Masick, BT; Trussell, C; Harris, JL Substrate optimization for monitoring cathepsin C activity in live cells. Bioorg Med Chem 17:1064-70 (2009) [PubMed]  Article 
Target
Name:
Pro-cathepsin H
Synonyms:
CATH_HUMAN | CBSP | CPSB | CTSH | Cathepsin H | Cathepsin H heavy chain | Cathepsin H light chain | Cathepsin H mini chain
Type:
PROTEIN
Mol. Mass.:
37402.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1459870
Residue:
335
Sequence:
MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
  
Inhibitor
Name:
BDBM50186088
Synonyms:
(S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)butanamide | (S)-2-amino-N-((S)-2-biphenyl-4-yl-1-cyano-ethyl)-butyramide | CHEMBL212521
Type:
Small organic molecule
Emp. Form.:
C19H21N3O
Mol. Mass.:
307.3895
SMILES:
CC[C@H](N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C#N |r|
Structure:
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