Reaction Details Report a problem with these data
Target
Thymidylate kinase
Ligand
BDBM1
Substrate
n/a
Meas. Tech.
ChEMBL_556416 (CHEMBL954908)
Ki
180000±n/a nM
Citation
 Gasse, C; Douguet, D; Huteau, V; Marchal, G; Munier-Lehmann, H; Pochet, S Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity. Bioorg Med Chem 16:6075-85 (2008) [PubMed]  Article 
Target
Name:
Thymidylate kinase
Synonyms:
CDC8 | DTYMK | KTHY_HUMAN | TMPK | TYMK
Type:
PROTEIN
Mol. Mass.:
23824.09
Organism:
Homo sapiens (Human)
Description:
ChEMBL_946051
Residue:
212
Sequence:
MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
  
Inhibitor
Name:
BDBM1
Synonyms:
dT | thymidine
Type:
Nucleoside or nucleotide
Emp. Form.:
C10H14N2O5
Mol. Mass.:
242.2286
SMILES:
Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: