Reaction Details Report a problem with these data
Target
Group 10 secretory phospholipase A2
Ligand
BDBM50262804
Substrate
n/a
Meas. Tech.
ChEMBL_489280 (CHEMBL990836)
IC50
10±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10
Type:
PROTEIN
Mol. Mass.:
18153.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1442449
Residue:
165
Sequence:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
  
Inhibitor
Name:
BDBM50262804
Synonyms:
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-6,7-benzoindol-4-yloxy)acetic acid | CHEMBL514705
Type:
Small organic molecule
Emp. Form.:
C27H26N2O5
Mol. Mass.:
458.5057
SMILES:
CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3ccccc3c2n1Cc1ccccc1
Structure:
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