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Target
Prostatic acid phosphatase
Ligand
BDBM50272138
Substrate
n/a
Meas. Tech.
ChEMBL_510106 (CHEMBL998760)
IC50
18±n/a nM
Citation
 Vovk, AI; Mischenko, IM; Tanchuk, VY; Kachkovskii, GA; Sheiko, SY; Kolodyazhnyi, OI; Kukhar, VP Stereoselectivity of binding of alpha-(N-benzylamino)benzylphosphonic acids to prostatic acid phosphatase. Bioorg Med Chem Lett 18:4620-3 (2008) [PubMed]  Article 
Target
Name:
Prostatic acid phosphatase
Synonyms:
ACP3 | ACPP | PPAP_HUMAN | Prostatic acid phosphatase
Type:
PROTEIN
Mol. Mass.:
44563.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_158625
Residue:
386
Sequence:
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
  
Inhibitor
Name:
BDBM50272138
Synonyms:
(R)-N-((S)-(4-methoxyphenyl)(phosphono)methyl)-1-phenylethanaminium chloride | CHEMBL507996
Type:
Small organic molecule
Emp. Form.:
C16H21NO4P
Mol. Mass.:
322.3155
SMILES:
COc1ccc(cc1)[C@@H]([NH2+][C@H](C)c1ccccc1)P(O)(O)=O |r|
Structure:
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