Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM50263913
Substrate
n/a
Meas. Tech.
ChEMBL_535597 (CHEMBL987071)
Ki
214±n/a nM
Citation
 Brown, A; Brown, L; Brown, TB; Calabrese, A; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent. Bioorg Med Chem Lett 18:5242-4 (2008) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM50263913
Synonyms:
5-(3-((2H-1,2,3-triazol-2-yl)methyl)-5-(4-ethoxy-3-methylphenyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL489387
Type:
Small organic molecule
Emp. Form.:
C20H21N7O2
Mol. Mass.:
391.4264
SMILES:
CCOc1ccc(cc1C)-c1nnc(Cn2nccn2)n1-c1ccc(OC)nc1
Structure:
Search PDB for entries with ligand similarity: