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Target
Vasopressin V2 receptor
Ligand
BDBM50263914
Substrate
n/a
Meas. Tech.
ChEMBL_535599 (CHEMBL987073)
Ki
6400±n/a nM
Citation
 Brown, A; Brown, L; Brown, TB; Calabrese, A; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent. Bioorg Med Chem Lett 18:5242-4 (2008) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
40295.28
Organism:
Homo sapiens (Human)
Description:
P30518
Residue:
371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
  
Inhibitor
Name:
BDBM50263914
Synonyms:
5-(3-(4-ethoxy-3-methylphenyl)-5-((2-methoxyethoxy)methyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL522255
Type:
Small organic molecule
Emp. Form.:
C21H26N4O4
Mol. Mass.:
398.4555
SMILES:
CCOc1ccc(cc1C)-c1nnc(COCCOC)n1-c1ccc(OC)nc1
Structure:
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