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Target
Vasopressin V1b receptor
Ligand
BDBM50263856
Substrate
n/a
Meas. Tech.
ChEMBL_535598 (CHEMBL987072)
Ki
>10000±n/a nM
Citation
 Brown, A; Brown, L; Brown, TB; Calabrese, A; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent. Bioorg Med Chem Lett 18:5242-4 (2008) [PubMed]  Article 
Target
Name:
Vasopressin V1b receptor
Synonyms:
AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor
Type:
Enzyme
Mol. Mass.:
46985.01
Organism:
Homo sapiens (Human)
Description:
P47901
Residue:
424
Sequence:
MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAETIIF
  
Inhibitor
Name:
BDBM50263856
Synonyms:
5-(3-(4-ethoxy-3-methylphenyl)-5-(ethoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL492029
Type:
Small organic molecule
Emp. Form.:
C20H24N4O3
Mol. Mass.:
368.4296
SMILES:
CCOCc1nnc(-c2ccc(OCC)c(C)c2)n1-c1ccc(OC)nc1
Structure:
Search PDB for entries with ligand similarity: