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Target
Melatonin receptor type 1A
Ligand
BDBM50263659
Substrate
n/a
Meas. Tech.
ChEMBL_535635 (CHEMBL987963)
Ki
275±n/a nM
Citation
 Poissonnier-Durieux, S; Ettaoussi, M; Pérès, B; Boutin, JA; Audinot, V; Bennejean, C; Delagrange, P; Caignard, DH; Renard, P; Berthelot, P; Lesieur, D; Yous, S Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands. Bioorg Med Chem 16:8339-48 (2008) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50263659
Synonyms:
CHEMBL476131 | N-[2-(3-(3-hydroxymethylphenyl)-7-methoxynaphth-1-yl)ethyl] acetamide
Type:
Small organic molecule
Emp. Form.:
C22H23NO3
Mol. Mass.:
349.4229
SMILES:
COc1ccc2cc(cc(CCNC(C)=O)c2c1)-c1cccc(CO)c1
Structure:
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