Target
Gamma-hydroxybutyrate receptor
Ligand
BDBM50246040
Substrate
n/a
Meas. Tech.
ChEMBL_558100 (CHEMBL956590)
IC50
500±n/a nM
Citation
 Molnár, TVisy, JSimon, AMoldvai, ITemesvári-Major, EDörnyei, GFekete, EKKardos, J Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes. Bioorg Med Chem Lett 18:6290-2 (2008) [PubMed]  Article 
Target
Name:
Gamma-hydroxybutyrate receptor
Synonyms:
Gamma hydroxybutyric, GHB | Gamma-hydroxybutyrate receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56171.11
Organism:
RAT
Description:
Gamma hydroxybutyric, GHB 0 RAT::Q6RY99
Residue:
512
Sequence:
MRAAAAGLGPGRLHAWAARRGLGRFPARVPRAAGGRSPCPASISNSRTLRLAAAGNTFCLASTLSSGCWEPCSWPSASGPGVRRAFFPTSQGGQIQGGLDPVWLFVVIGGIMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIRTSTALTSNPSRERCGVPFFCWVRTLRKTSQYPCGYTSAQTELEHKIHLHQSWWPFEKWLKKPDGWPGLGAIASFKMGIAGPNPRSTSRQERPTGKLPGVMATCLAHRAVVGASKDALPHSQWQGLWDVCYDLSPRLCEHGTQEATEAGLGLNWGCTGAGLGLFTTELCVWGVHMCVCVCVCVCVRVCLCLCVRVRGMHVCALVSTPGVSTPLLVRWWPFQSFKGDGARRVGHVPASPSLLWDVSLCGLGACCLRPLHIHHDLEPAWSSPWPQCHSLEMGPRILSVSLSRLPLRTHTWQDGYERLN
  
Inhibitor
Name:
BDBM50246040
Synonyms:
(E,RS)-(6,7,8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylidene)acetic acid | 6,7,8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylideneacetic acid | CHEMBL472694
Type:
Small organic molecule
Emp. Form.:
C13H14O3
Mol. Mass.:
218.2485
SMILES:
OC1c2ccccc2CCC\C1=C/C(O)=O
Structure:
Search PDB for entries with ligand similarity: