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Target
Gamma-hydroxybutyrate receptor
Ligand
BDBM50246038
Substrate
n/a
Meas. Tech.
ChEMBL_558101 (CHEMBL956591)
IC50
800±n/a nM
Citation
 Molnár, T; Visy, J; Simon, A; Moldvai, I; Temesvári-Major, E; Dörnyei, G; Fekete, EK; Kardos, J Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes. Bioorg Med Chem Lett 18:6290-2 (2008) [PubMed]  Article 
Target
Name:
Gamma-hydroxybutyrate receptor
Synonyms:
Gamma hydroxybutyric, GHB | Gamma-hydroxybutyrate receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56171.11
Organism:
RAT
Description:
Gamma hydroxybutyric, GHB 0 RAT::Q6RY99
Residue:
512
Sequence:
MRAAAAGLGPGRLHAWAARRGLGRFPARVPRAAGGRSPCPASISNSRTLRLAAAGNTFCLASTLSSGCWEPCSWPSASGPGVRRAFFPTSQGGQIQGGLDPVWLFVVIGGIMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIRTSTALTSNPSRERCGVPFFCWVRTLRKTSQYPCGYTSAQTELEHKIHLHQSWWPFEKWLKKPDGWPGLGAIASFKMGIAGPNPRSTSRQERPTGKLPGVMATCLAHRAVVGASKDALPHSQWQGLWDVCYDLSPRLCEHGTQEATEAGLGLNWGCTGAGLGLFTTELCVWGVHMCVCVCVCVCVRVCLCLCVRVRGMHVCALVSTPGVSTPLLVRWWPFQSFKGDGARRVGHVPASPSLLWDVSLCGLGACCLRPLHIHHDLEPAWSSPWPQCHSLEMGPRILSVSLSRLPLRTHTWQDGYERLN
  
Inhibitor
Name:
BDBM50246038
Synonyms:
(R)-2-(5-hydroxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-ylidene)acetic acid | CHEMBL514926
Type:
Small organic molecule
Emp. Form.:
C13H14O3
Mol. Mass.:
218.2485
SMILES:
O[C@H]1c2ccccc2CCC\C1=C/C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: