Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 1
Ligand
BDBM50267114
Substrate
n/a
Meas. Tech.
ChEMBL_565116 (CHEMBL965760)
IC50
38700±n/a nM
Citation
 Cao, S; Murphy, BT; Foster, C; Lazo, JS; Kingston, DG Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorg Med Chem 17:2276-81 (2009) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
3ch134 | DUS1_MOUSE | Dusp1 | Mkp1 | Ptpn10 | Ptpn16
Type:
PROTEIN
Mol. Mass.:
39372.46
Organism:
Mus musculus
Description:
ChEMBL_565116
Residue:
367
Sequence:
MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC
  
Inhibitor
Name:
BDBM50267114
Synonyms:
1,1-Dioxo-1,2,3,4,7,8,9,10-octahydro-1lambda6-thia-4-aza-naphthacene-5,12-dione | CHEMBL476655
Type:
Small organic molecule
Emp. Form.:
C16H15NO4S
Mol. Mass.:
317.36
SMILES:
O=C1C2C(=NCCS2(=O)=O)C(=O)c2cc3CCCCc3cc12 |c:3|
Structure:
Search PDB for entries with ligand similarity: