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Target
Cannabinoid receptor 1
Ligand
BDBM50256271
Substrate
n/a
Meas. Tech.
ChEMBL_515074 (CHEMBL1034816)
IC50
81.9±n/a nM
Citation
 Hou, DR; Alam, S; Kuan, TC; Ramanathan, M; Lin, TP; Hung, MS 1,2,3-Triazole derivatives as new cannabinoid CB1 receptor antagonists. Bioorg Med Chem Lett 19:1022-5 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50256271
Synonyms:
2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-yl)-N-(4-methoxybenzyl)acetamide | CHEMBL480539
Type:
Small organic molecule
Emp. Form.:
C24H18Cl4N4O2
Mol. Mass.:
536.237
SMILES:
COc1ccc(CNC(=O)Cn2nc(c(n2)-c2ccc(Cl)cc2Cl)-c2ccc(Cl)cc2Cl)cc1
Structure:
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