Reaction Details Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM26994
Substrate
n/a
Meas. Tech.
ChEMBL_515684 (CHEMBL993072)
Ki
90000±n/a nM
Citation
 Bertucci, A; Innocenti, A; Zoccola, D; Scozzafava, A; Allemand, D; Tambutté, S; Supuran, CT Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions. Bioorg Med Chem Lett 19:650-3 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Homo sapiens (Human)
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM26994
Synonyms:
CHEMBL68253 | H2NSO3H | sulfamic acid
Type:
n/a
Emp. Form.:
H3NO3S
Mol. Mass.:
97.094
SMILES:
NS(O)(=O)=O
Structure:
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