Reaction Details Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM26996
Substrate
n/a
Meas. Tech.
ChEMBL_515684 (CHEMBL993072)
Ki
820000±n/a nM
Citation
 Bertucci, A; Innocenti, A; Zoccola, D; Scozzafava, A; Allemand, D; Tambutté, S; Supuran, CT Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions. Bioorg Med Chem Lett 19:650-3 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Homo sapiens (Human)
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM26996
Synonyms:
CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phenylboronic acid, 22 | benzeneboronic acid | phenylboranediol | phenylboronic acid
Type:
n/a
Emp. Form.:
C6H7BO2
Mol. Mass.:
121.93
SMILES:
OB(O)c1ccccc1
Structure:
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