Reaction Details Report a problem with these data
Target
Testis-specific serine/threonine-protein kinase 1
Ligand
BDBM50279385
Substrate
n/a
Meas. Tech.
ChEMBL_545767 (CHEMBL1027662)
IC50
43200±n/a nM
Citation
 Zhang, L; Yan, Y; Liu, Z; Abliz, Z; Liu, G Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays. J Med Chem 52:4419-28 (2009) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 1
Synonyms:
SPOGA1 | SPOGA4 | STK22A | STK22D | TSSK1 | TSSK1B | TSSK1_HUMAN | Testis-specific serine/threonine-protein kinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41624.03
Organism:
Homo sapiens (Human)
Description:
gi_14042947
Residue:
367
Sequence:
MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
  
Inhibitor
Name:
BDBM50279385
Synonyms:
1,1'-(biphenyl-4,4'-diyl)bis(2,2-dihydroxyethanone) | CHEMBL454274
Type:
Small organic molecule
Emp. Form.:
C16H14O6
Mol. Mass.:
302.2788
SMILES:
OC(C(O)=O)c1ccc(cc1)-c1ccc(cc1)C(O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: