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Target
Testis-specific serine/threonine-protein kinase 1
Ligand
BDBM50278920
Substrate
n/a
Meas. Tech.
ChEMBL_545769 (CHEMBL1027664)
IC50
38000±n/a nM
Citation
 Zhang, L; Yan, Y; Liu, Z; Abliz, Z; Liu, G Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays. J Med Chem 52:4419-28 (2009) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 1
Synonyms:
SPOGA1 | SPOGA4 | STK22A | STK22D | TSSK1 | TSSK1B | TSSK1_HUMAN | Testis-specific serine/threonine-protein kinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41624.03
Organism:
Homo sapiens (Human)
Description:
gi_14042947
Residue:
367
Sequence:
MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETRAQ
  
Inhibitor
Name:
BDBM50278920
Synonyms:
4-(7-isopropyl-6-oxo-1-(3-phenylpropyl)-5,6-dihydro-1H-imidazo[4,5-g]quinoxalin-2-yl)benzoic acid | CHEMBL497881
Type:
Small organic molecule
Emp. Form.:
C28H26N4O3
Mol. Mass.:
466.531
SMILES:
CC(C)c1nc2cc3n(CCCc4ccccc4)c(nc3cc2[nH]c1=O)-c1ccc(cc1)C(O)=O
Structure:
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