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Target
Alpha-(1,3)-fucosyltransferase 10
Ligand
BDBM50421339
Substrate
n/a
Meas. Tech.
ChEBML_69135
IC50
>125000000±n/a nM
Citation
 Dumas, DP; Ichikawa, Y; Wong, CH; Lowe, JB; Nair, RP Enzymatic synthesis of sialyl Lex and derivatives based on a recombinant fucosyltransferase Bioorg Med Chem Lett 1:425-428 (1991)    Article 
Target
Name:
Alpha-(1,3)-fucosyltransferase 10
Synonyms:
FUT10 | FUT10_HUMAN | Fucosyltransferase 10
Type:
PROTEIN
Mol. Mass.:
56106.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_69135
Residue:
479
Sequence:
MVRIQRRKLLASCLCVTATVFLLVTLQVMVELGKFERKEFKSSSLQDGHTKMEEAPTHLNSFLKKEGLTFNRKRKWELDSYPIMLWWSPLTGETGRLGQCGADACFFTINRTYLHHHMTKAFLFYGTDFNIDSLPLPRKAHHDWAVFHEESPKNNYKLFHKPVITLFNYTATFSRHSHLPLTTQYLESIEVLKSLRYLVPLQSKNKLRKRLAPLVYVQSDCDPPSDRDSYVRELMTYIEVDSYGECLRNKDLPQQLKNPASMDADGFYRIIAQYKFILAFENAVCDDYITEKFWRPLKLGVVPVYYGSPSITDWLPSNKSAILVSEFSHPRELASYIRRLDSDDRLYEAYVEWKLKGEISNQRLLTALRERKWGVQDVNQDNYIDAFECMVCTKVWANIRLQEKGLPPKRWEAEDTHLSCPEPTVFAFSPLRTPPLSSLREMWISSFEQSKKEAQALRWLVDRNQNFSSQEFWGLVFKD
  
Inhibitor
Name:
BDBM50421339
Synonyms:
CHEMBL2303753
Type:
Small organic molecule
Emp. Form.:
C12H20O9
Mol. Mass.:
308.2818
SMILES:
OC[C@@H]1O[C@@H](O[C@H]2[C@H](O)C=CO[C@H]2CO)[C@@H](O)[C@@H](O)[C@H]1O |r,c:9|
Structure:
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