Reaction Details Report a problem with these data
Target
Alpha-(1,3)-fucosyltransferase 10
Ligand
BDBM50421340
Substrate
n/a
Meas. Tech.
ChEBML_69135
IC50
>125000000±n/a nM
Citation
 Dumas, DP; Ichikawa, Y; Wong, CH; Lowe, JB; Nair, RP Enzymatic synthesis of sialyl Lex and derivatives based on a recombinant fucosyltransferase Bioorg Med Chem Lett 1:425-428 (1991)    Article 
Target
Name:
Alpha-(1,3)-fucosyltransferase 10
Synonyms:
FUT10 | FUT10_HUMAN | Fucosyltransferase 10
Type:
PROTEIN
Mol. Mass.:
56106.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_69135
Residue:
479
Sequence:
MVRIQRRKLLASCLCVTATVFLLVTLQVMVELGKFERKEFKSSSLQDGHTKMEEAPTHLNSFLKKEGLTFNRKRKWELDSYPIMLWWSPLTGETGRLGQCGADACFFTINRTYLHHHMTKAFLFYGTDFNIDSLPLPRKAHHDWAVFHEESPKNNYKLFHKPVITLFNYTATFSRHSHLPLTTQYLESIEVLKSLRYLVPLQSKNKLRKRLAPLVYVQSDCDPPSDRDSYVRELMTYIEVDSYGECLRNKDLPQQLKNPASMDADGFYRIIAQYKFILAFENAVCDDYITEKFWRPLKLGVVPVYYGSPSITDWLPSNKSAILVSEFSHPRELASYIRRLDSDDRLYEAYVEWKLKGEISNQRLLTALRERKWGVQDVNQDNYIDAFECMVCTKVWANIRLQEKGLPPKRWEAEDTHLSCPEPTVFAFSPLRTPPLSSLREMWISSFEQSKKEAQALRWLVDRNQNFSSQEFWGLVFKD
  
Inhibitor
Name:
BDBM50421340
Synonyms:
CHEMBL2303756
Type:
Small organic molecule
Emp. Form.:
C17H29NO10
Mol. Mass.:
407.4129
SMILES:
CC(=O)N[C@H]1C[C@H](O[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)[C@H](CO)O[C@@H]1OCC=C |r|
Structure:
Search PDB for entries with ligand similarity: