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Target
Adenosine receptor A1
Ligand
BDBM50281149
Substrate
n/a
Meas. Tech.
ChEBML_29639
Ki
390±n/a nM
Citation
 Knutsen, LJ; Lau, J; Sheardown, MJ; Thomsen, C The synthesis and biochemical evaluation of new A1 selective adenosine receptor agonists containing 6-hydrazinopurine moieties Bioorg Med Chem Lett 3:2661-2666 (1993)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50281149
Synonyms:
(2R,3S,4R,5R)-2-Hydroxymethyl-5-[2-methylsulfanyl-6-(piperidin-1-ylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL329189
Type:
Small organic molecule
Emp. Form.:
C16H24N6O4S
Mol. Mass.:
396.465
SMILES:
CSc1nc(NN2CCCCC2)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
Structure:
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