Reaction Details Report a problem with these data
Target
Scytalone dehydratase
Ligand
BDBM50282107
Substrate
n/a
Meas. Tech.
ChEMBL_199537 (CHEMBL801406)
pH
7±n/a
Ki
6700±n/a nM
Comments
extracted
Citation
 Hodge, C; Pierce, J A diazine heterocycle replaces a six-membered hydrogen-bonded array in the active site of scytalone dehydratase Bioorg Med Chem Lett 3:1605-1608 (1993)    Article 
Target
Name:
Scytalone dehydratase
Synonyms:
SCYD_MAGO7 | SDH1 | Scytalone dehydratase
Type:
PROTEIN
Mol. Mass.:
20248.63
Organism:
Magnaporthe grisea
Description:
ChEMBL_199536
Residue:
172
Sequence:
MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK
  
Inhibitor
Name:
BDBM50282107
Synonyms:
CHEMBL289792 | Isoquinolin-1-yl-(3-phenyl-propyl)-amine
Type:
Small organic molecule
Emp. Form.:
C18H18N2
Mol. Mass.:
262.3489
SMILES:
C(CNc1nccc2ccccc12)Cc1ccccc1
Structure:
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