Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50283330
Substrate
n/a
Meas. Tech.
ChEBML_201298
Ki
8±n/a nM
Citation
 Christos, TE; Cain, GA; Johnson, AL; Schmidt, WK; Tam, SW Novel ether derivatives of alkyl piperidines as potential sigma / 5HT2 antipsychotic agents Bioorg Med Chem Lett 4:2347-2352 (1994)    Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50283330
Synonyms:
1-((E)-But-2-enyl)-4-((E)-3-phenyl-allyloxymethyl)-piperidine | CHEMBL76475
Type:
Small organic molecule
Emp. Form.:
C19H27NO
Mol. Mass.:
285.4238
SMILES:
C\C=C\CN1CCC(COC\C=C\c2ccccc2)CC1
Structure:
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