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Target
Kappa-type opioid receptor
Ligand
BDBM50283522
Substrate
n/a
Meas. Tech.
ChEMBL_92402 (CHEMBL701396)
IC50
11000±n/a nM
Citation
 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U Palladium-catalyzed synthesis of C3-substituted 3-deoxymorphines. Bioorg Med Chem Lett 4:2527-2532 (1994)    Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50283522
Synonyms:
4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-ol | CHEMBL85457
Type:
Small organic molecule
Emp. Form.:
C17H19NO2
Mol. Mass.:
269.3383
SMILES:
CN1CC[C@]23[C@H]4Oc5cccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35 |c:17|
Structure:
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