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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50283812
Substrate
n/a
Meas. Tech.
ChEBML_79969
Ki
160±n/a nM
Citation
 Ettmayer, P; Hübner, M; Andreas, B; Brigitte, R; Hubert, G Novel, extended transition state mimic in HIV-1 protease inhibitors with peripheral C-2-symmetry Bioorg Med Chem Lett 4:2851-2856 (1994)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50283812
Synonyms:
(S)-2-(3-1H-Benzoimidazol-2-yl-propionylamino)-N-{(1S,2R,3R,4S)-4-[(S)-2-(3-1H-benzoimidazol-2-yl-propionylamino)-3,3-dimethyl-butyrylamino]-1-benzyl-3-hydroxy-2-hydroxymethyl-5-phenyl-pentyl}-3,3-dimethyl-butyramide | CHEMBL407000
Type:
Small organic molecule
Emp. Form.:
C51H64N8O6
Mol. Mass.:
885.1039
SMILES:
CC(C)(C)[C@H](NC(=O)CCc1nc2ccccc2[nH]1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)[C@@H](CO)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CCc1nc2ccccc2[nH]1)C(C)(C)C
Structure:
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