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Target
Cholecystokinin receptor type A
Ligand
BDBM50284160
Substrate
n/a
Meas. Tech.
ChEBML_49404
IC50
430±n/a nM
Citation
 Batt, AR; Kendrick, DA; Mathews, E; Rooker, DP; Ryder, H; Semple, G; Szelke, M Novel cholecystokinin receptor ligands: Oxopiperazines derived from Boc-CCK-4 Bioorg Med Chem Lett 4:867-872 (1994)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR_MOUSE | Cckar | Cholecystokinin A receptor | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
PROTEIN
Mol. Mass.:
48454.29
Organism:
Mus musculus
Description:
ChEMBL_40042
Residue:
436
Sequence:
MDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSAVQILLYSFIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLIPGVVMVVAYGLISLELYQGIKFDASQKKSAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGRINRIRSSGSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPTGVRGEVGEEEDGRTIRASLSRYSYSHMSTSAPPH
  
Inhibitor
Name:
BDBM50284160
Synonyms:
CHEMBL169178 | [(S)-1-[(S)-1-((S)-3-Benzyl-5-oxo-piperazine-1-carbonyl)-3-methyl-butylcarbamoyl]-2-(1H-indol-3-yl)-ethyl]-carbamic acid ethyl ester
Type:
Small organic molecule
Emp. Form.:
C31H39N5O5
Mol. Mass.:
561.6719
SMILES:
CCOC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N1C[C@H](Cc2ccccc2)NC(=O)C1
Structure:
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