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Target
Peroxisomal carnitine O-octanoyltransferase
Ligand
BDBM50284163
Substrate
n/a
Meas. Tech.
ChEMBL_46183 (CHEMBL660927)
IC50
475000±n/a nM
Citation
 Kumaravel, G; Bháird, NN; Fronczek, FR; Ramsay, RR; Ashendel, CL; Gandour, RD Evaluation of (2S,4S)/(2R,4R) and (2S,4R)/(2<... Bioorg Med Chem Lett 4:883-886 (1994)    Article 
Target
Name:
Peroxisomal carnitine O-octanoyltransferase
Synonyms:
OCTC_HUMAN | CROT | COT
Type:
PROTEIN
Mol. Mass.:
70184.70
Organism:
Human
Description:
ChEMBL_46182
Residue:
612
Sequence:
MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL
  
Inhibitor
Name:
BDBM50284163
Synonyms:
(S)-4-Hexadecyl-2,6,6-trimethyl-2-oxo-2lambda*5*-[1,3,6,2]dioxazaphosphocan-6-ium; bromide | CHEMBL170076
Type:
Small organic molecule
Emp. Form.:
C23 H49 N O3 P . Br
Mol. Mass.:
498.51782
SMILES:
CCCCCCCCCCCCCCCCC1C[N+](C)(C)CCO[P@](C)(=O)O1
Structure:
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