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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50286123
Substrate
n/a
Meas. Tech.
ChEMBL_157866 (CHEMBL764969)
Ki
0.067000±n/a nM
Citation
 Wilkerson, WW; Hollis, AY; Cheatham, WW; Lam, GN; Erickson-Viitanen, S; Bacheler, L; Cordova, BC; Klabe, RM; Meek, JL A bis-[N-3-(1-hydroxy-1-methyl-ethyl)-benzyl)-cyclic urea as a HIV protease inhibitor Bioorg Med Chem Lett 5:3027-3032 (1995)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50286123
Synonyms:
(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1,3-bis-[3-(1-hydroxy-1-methyl-ethyl)-benzyl]-[1,3]diazepan-2-one | CHEMBL431831
Type:
Small organic molecule
Emp. Form.:
C39H46N2O5
Mol. Mass.:
622.7929
SMILES:
CC(C)(O)c1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3cccc(c3)C(C)(C)O)C2=O)c1
Structure:
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