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Target
Dopamine beta-hydroxylase
Ligand
BDBM50286809
Substrate
n/a
Meas. Tech.
ChEBML_59304
Ki
1010000±n/a nM
Citation
 Eydoux, F; Chlenov, MA; Réglier, M Synthesis of indane derivatives as mechanism-based inhibitors of dopamine β-hydroxylase Bioorg Med Chem Lett 5:941-944 (1995)    Article 
Target
Name:
Dopamine beta-hydroxylase
Synonyms:
DBH | DOPO_BOVIN
Type:
PROTEIN
Mol. Mass.:
68136.39
Organism:
Bos taurus
Description:
ChEMBL_50738
Residue:
610
Sequence:
MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISYAQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDSQQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSGLHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIVMYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMELGLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARDGRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSFNREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGPTVLNISGGKG
  
Inhibitor
Name:
BDBM50286809
Synonyms:
7,7a-Dihydro-1aH-1,3,5-trioxa-cyclopropa[a]-s-indacene | CHEMBL426223
Type:
Small organic molecule
Emp. Form.:
C10H8O3
Mol. Mass.:
176.1687
SMILES:
C1Oc2cc3CC4OC4c3cc2O1
Structure:
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