Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50287811
Substrate
n/a
Meas. Tech.
ChEBML_46464
Ki
>20000±n/a nM
Citation
 Gallant, M; Dufresne, C; Gareau, Y; Guay, D; Leblanc, Y; Prasit, P; Rochette, C; Sawyer, N; Slipetz, DM; Tremblay, N; Metters, KM; Labelle, M New class of potent ligands for the human peripheral cannabinoid receptor Bioorg Med Chem Lett 6:2263-2268 (1996)    Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50287811
Synonyms:
2-[1-(2,3-Dichloro-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-morpholin-4-yl-ethanone | CHEMBL308847
Type:
Small organic molecule
Emp. Form.:
C23H24Cl2N2O3
Mol. Mass.:
447.354
SMILES:
COc1ccc2n(Cc3cccc(Cl)c3Cl)c(C)c(CC(=O)N3CCOCC3)c2c1
Structure:
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